The HivE Lab researches information encoding in the medial prefrontal cortex (mPFC), hippocampus (HC), and connected areas. Our lab records the activity of large ensembles of single neurons, along with oscillatory activity in multiple brain areas, while rodents complete an array of cognitive, emotional and memory taxing tasks.

This is the hyperdrive recording implant used to listen to firing neurons

We use advanced mathematical techniques to unravel the complex neural coding schemes employed to convey information related to reward probability, behavioral context, working memory, tracking time and outcome expectancy. Additional research topics concentrate on interactions between the mPFC and multiple other neural areas including: the hippocampal long term memory system, the ventral tegmental area reward circuit, the locus coeruleus attentional system and the amygdalar emotional response system. 

The video bellow demonstrates the anterior cingulate cortex activity during multi behavior sequence task


Jefferson Kinney, Ph.D.


Edwin Oh, Ph.D.


Cleveland Clinic Lou Ruvo Center for Brain Health